Drug Target Review

Logic-gated DARPins show targeted T-cell activation in tumours

Learn how Logic-gated DARPins work to activate T cells selectively in solid tumours, enhancing therapeutic outcomes.
Nanowerk

Equipping living cells with logic gates to fight cancer

(Nanowerk News) One of the most exciting developments in cancer treatment is a wave of new cell therapies that train a patient’s immune system to attack cancer cells. Such therapies have saved the ...
Science Daily

Using cancer cells as logic gates to determine what makes them move

Researchers have reverse-engineered a cellular signal processing system and used it like a logic gate -- a simple computer -- to better understand what causes specific cells to migrate. Cancer cells ...
Seeking Alpha

Senti Bio’s SENTI-202, a First-in-Class Off-the-Shelf Logic Gated Selective CD33 OR FLT3 NOT EMCN CAR NK Cell Therapy, Demonstrates Positive Preliminary Clinical Results in ...

SOUTH SAN FRANCISCO, Calif., April 28, 2025 (GLOBE NEWSWIRE) -- Senti Biosciences, Inc. (SNTI) (“Senti Bio” or the “Company”), a clinical-stage biotechnology company developing next-generation cell ...
manilatimes

Senti Bio to Present Updated Clinical Results of First-in-Class Logic Gated CD33/FLT3 Cell Therapy, SENTI-202, at the American Society of Hematology (ASH) Annual Meeting 2025

Two presentations, including one oral session, build on existing data and show deep and durable clinical remission rates, combined with a strong safety profile, for SENTI-202 in treating ...
EurekAlert!

Using cancer cells as logic gates to determine what makes them move

Cancer cells migrate through the body for multiple reasons; some are simply following the flow of a fluid, while others are actively following specific chemical trails. So how do you determine which ...